1. Success rates
An individual couple’s chance of success depends on a number of factors such as the cause of infertility, age and lifestyle.
As a general guide, there is a 50 per cent chance of conception per IVF treatment if aged under 30. This goes down to a 20 per cent chance for your first IVF treatment over the age of 40.
2. When women's fertility really starts to drop
A woman’s fertility starts to drop dramatically from the age of 35. Diminishing egg numbers is one issue, diminishing quality is just as important. Again, egg quality starts to decline from age 35.
A simple blood test, known as AMH, will tell a woman if she has a normal number of eggs for her age but tells us little about the quality of the eggs remaining.
3. Men's fertility can also reduce with age
While women are born with all the eggs they will ever have, men are continually producing new sperm. However, as men age, the quality of the genes in their sperm deteriorates.
After a woman’s age, male infertility is the single largest factor influencing a couples chance to conceive. Problems include increased DNA damage, irregular shape and reduced quantity and movement. This becomes more common in men over the age of 50.
There is also evidence linking older fathers with increased risk of their child being affected by rare genetic disorders such as autism.
4. Rise of infertility
According to Dr Ann Tan and Tanja Faessler-Moro from Virtus Fertility Centre, with an increasingly informed population, both men and women, are now more willing to get tested for fertility. As such, more cases are being discovered and this contributes to the apparent rise of infertility in Singapore.
5. The physical and emotional cost
Many women describe the experience of IVF as physically and emotionally demanding.
Physical side effects can include headaches, tiredness, bloating and mood swings.
Many find the experience stressful as they anxiously await the outcome.
Reputable clinics offer specially trained and qualified counsellors to help people through the emotionally challenging aspects of IVF.
There are two main IVF treatment cycles — a short cycle known as an antagonist cycle which takes about four weeks with treatment commencing on the first day of a woman’s period; or the more common agonist cycle, which takes about five weeks with hormone suppression commencing on day 22 of a woman’s cycle.
Patients must wait two weeks following the transfer of an embryo to the womb for a blood test to confirm pregnancy.
7. You can't cheat age (or the age of your eggs)
A woman is at her most fertile in her twenties and early thirties. Fertility specialists around the world are working hard on perfecting a technique to freeze eggs so that a woman can have a child at a time when she is ready.
To date, this is still regarded as experimental and is mainly offered to women about to undergo chemotherapy or other medical procedures that will affect their future fertility.
8. The increase of reliance
Social changes mean couples are leaving it later in life to have children and more and more are turning to IVF for help to conceive.
However, there is no evidence to suggest that women are deliberately delaying having children because of IVF. They are simply waiting until they have met Mr Right and are financially able to meet the costs of child-rearing.
IVF has been around for more than 30 years. It is a very safe procedure, with no long-term risks to mother or child. The most serious medical complication is Ovulation Hyperstimulation Syndrome (OHSS), affecting one percent of women.
It occurs when a woman over-responds to hormone treatment and produces too many eggs. However, the lower drug doses used nowadays mean that this is much less common. In addition, specialists have become much better at predicting which woman are at risk of OHSS, and the medical profession is well trained in recognising and managing symptoms.
10. There are no guarantees
IVF is a highly effective treatment in overcoming many causes of infertility such as low sperm count, blocked fallopian tubes and PCOS. However, there are no guarantees.
In fact, it is estimated that half of the people who try IVF will not be successful. Counselling has helped thousands of people come to terms with a life without hope for a family, and counselling is recommended when couples face the difficult decision to stop treatment.